Cell-based Gene Therapy for Premature Ovarian Failure (POF), Mrs. Wei from China

Name: Mrs. Wei
Age: 39 years old
Gender: Female
Nationality: China
Diagnosis: Premature Ovarian Failure, Obesity
Therapy: Cell-based Gene Therapy (HGF and adipose-derived stem cells), TCM (Acupuncture and Chinese massage)

Conditions before Cell-based Gene Therapy for Premature Ovarian Failure

Mrs. Wei is a 39 years old female from China. She was married for 7 years but was unable to conceive a child. Mrs. Wei was diagnosed with premature ovarian failure when she was 19 years old caused by endocrine disorder, polycystic ovary syndrome, and she had amenorrhea ever since then. During the 20 years of her amenorrhea, she had tried various medications such as progesterone and Clomipramine to maintain her menstruation, but too little effect was shown. Mrs. Wei also faced obesity besides POF. She was weighted 90 kg and experienced severe acne. As she grew older, she suffered more and worse symptoms, including her night sweat, hot flashes and vaginal dryness.

Therapy and Procedure

Cell-based gene therapy (HGF and adipose-derived stem cells): 2 sessions (4 weeks in total) and TCM (Acupuncture and Chinese massage)

Conditions after Cell-based Gene Therapy for Premature Ovarian Failure

One month after the first session of cell-based gene therapy, Mrs. Wei lost 10 kg of weight. The acne on her face got improved. Although her night sweat and hot flashes still remained, she could feel that they have ceased from further deterioration and her vaginal dryness condition was better compared with before. Her menstruation became normal with the treatment. As the first session has showed effective result, Mrs. Wei immediately proceeded to second session.

Two months after the second session, Mrs. Wei’s weight has dropped to 70kg. She looked much slimmer than before and her acne was basically disappeared. Her POF symptoms such as night sweat, hot flashes and vaginal dryness have been relieved obviously. Besides the improvement on her symptoms, Mrs. Wei’s menstruation keeps regular without the treatment.

Follow Up

Two months after Mrs. Wei received cell-based gene therapy for her POF, her menstruation stopped suddenly. Mrs. Wei triedHer HCG test which was positive. Mrs. Wei could not believe that, thus she has changed three different brands of pee stick for HCG test. However, the three tests were still showing positive result (pregnant). For further confirmation, Mrs. Wei underwent a B-ultrasound scan. The result confirmed that she was pregnant for two months. Her whole family was so thrilled.

Seven month after the birth of her first son, follow-up with Mrs. Wei showed that she was pregnant again for over a month…