Patient Name: Sebiha
Days Admitted to Hospital: 21 days
Treatment: Stem Cell Therapy, Traditional Chinese Medicine and Supportive Treatment.
Motor neuron disease: Amyotrophic Lateral Sclerosis;
Hypertension Ⅲ(extremely high risk)
Obsolescence of cerebral infarction
Our patient Sebiha is a beautiful lady who has three children. She has been suffering from limited mobility of upper and lower limbs for one and half years. She has turned to ReLife International Medical Center to require hospitalization to receive Mesenchymal Stem Cells Therapy and Traditional Chinese Medicine. In May, 2013, the patient started to notice the weakness of her right foot without obvious precipitating factors, and her mobility was limited. Her condition was gradually worsened. Symptom gradually spread from distal to proximal limb. Within three months, her condition gradually progressed to the entire right leg. In January 2014, limitation of motion appeared in her left leg, six months later, she was paralyzed in lower limbs, and thus she was confined in bed. In September, 2014, she began to feel weakness in her right hand; it was difficult for her to raise her left arm. MRI for nervous system showed multiple small infarctions in the brain. (Specific medications were unknown). One month later, the symptom progressed to the left upper limb. After having undergoing several physical check-ups in local hospitals, her diagnosis had still not been confirmed until May 2014, After considering the progression of the disease, doctors in local hospital considered her case to be motor neuron disease, and prescribed her Riluzole, ordered her to take 2 times per day until now, 50mg per time. However her condition was still progressing. Since her first complaint, the patient was conscious, without difficulty in speaking and communication, her pronunciation clear, occasionally choke while drinking; her sleep and appetite was normal, urine was normal, she has been suffering from constipation for nearly 3 months and has stool once every 2 to 3 days, her weight loss was obvious since the onset of her illness.
Medical Condition before Stem Cell Treatment
The patient grew normally, with normal nutrition, normal appearance, natural expression. She was lying on the bed, sane, clear pronunciation; cooperate with doctors while doing physical examination. No dry and wet rales were heard in both lungs; heart rate 74 T / min, heart rate even, no noise was heard in each valve auscultation area, Abdomen was soft, and liver and spleen untouched; Her spine has natural curves. Muscle strength of right upper arm graded II, and that of right forearm gradedⅡ-Ⅲ, grip strength of right hand graded III. Muscle strength of left upper limb graded III, and grip strength of left hand graded III. The activities of both arms and both shoulder joint were limited. Muscle strength of lower limbs graded 0-Ⅰ. Muscle tone of arms and legs was remarkably decreased; reflexes decreased on bilateral biceps, triceps and radial membrane tendon. Reflexes of Tendon and knees were weakened. Bilateral Babinski: negative. Bilateral Hoffmann: negative. Bilateral palm jaw reflex was suspected positive; No abnormal was found in extremities. The deep sensibility of extremities was normal as well as position sense.
Stem Cell Treatment & TCM for Twenty-One Days
After admission, several medical protocols were applied, including: MSC (Mesenchymal Stem Cell) Therapy combined with Traditional Chinese Medicine (acupuncture, Chinese massage, Chinese herbal soup) and Supportive Treatment.
Medical Condition after Stem Cell Treatment
The patient is alert, normal spirit; sleep not so good, fluent speaking. Muscle strength of limbs has improved slightly. Physical Examination: the breath sounds in the lung is normal without rales and rhonchi; there is no pleural friction sound, regular heartbeat with heat rate 74 T/m; auscultatory valve areas were not murmur sounds; the abdomen is soft, liver and spleen were impalpable. The muscle strength on the right upper arm grades Ⅱ+, the muscle strength on the right forearm grades Ⅲ, the grip strength on the right hand grades Ⅲ; The muscle strength on the left upper arm grades Ⅲ, the muscle strength on the forearm grades Ⅲ+, the grip strength on the right hand grades Ⅲ+; The limitation of shoulder joint activity function has alleviated. Both lower limbs muscle strength grades Ⅰ. Muscular tension on limbs has reduced. The tendon reflex on bilateral biceps brachii, triceps brachii and radial periosteal has reduced; the patellar tendon reflex and Achilles tendon reflex also have reduced. None abnormality indicated on the sensory of extremities. Bathyesthesia and position sense of extremities were normal.